MRI新技术在中枢神经系统疾病的应用及智能影像诊断
现在承担和参与的课题：
科研项目名称 | 金额（万） | 课题来源 | 执行情况 | 本人排名 |
面向多模态医学数据开放共享的数据治理解决方案 | 200 | 上海市科学技术委员会 人工智能支撑项目 | 在研 | 1 |
基于多模态磁共振成像技术研究MELAS卒中样发作的中枢性损伤及其机制 | 20 | 上海市科学技术委员会 自然基金面上项目 | 在研 | 1 |
基于MRA影像的脑动脉瘤自动检测与风险评估系统 | 20 | 复旦大学医工结合项目 | 在研 | 共同负责人 |
DTI联合DKI动态研究多发性硬化的髓鞘再生及相关神经修复机制 | 23 | 国家自然科学基金 青年项目 | 结题 | 1 |
基于异构医学影像数据的深度挖掘技术及中枢神经系统重大疾病的精准预测 | 64 | 国家自然科学基金 面上项目 | 结题 | 2 |
脑卒中多中心多模态影像数据库的建立及人工智能产品的评价体系研究 | 200 | 上海市科学技术委员会“科技创新行动计划 | 在研 | 2 |
申请专利情况
第一发明人申请专利1项，参与发明申请专利6项，软件著作2项
［1］2015年国家科技进步二等奖，排名6
［2］2013年上海市科技进步一等奖，排名5
［3］2012年教育部高等学校科技进步一等奖，排名2
［4］ 2012年中华医学科技奖三等奖，排名2
［5］ 2008年上海医学科技奖二等奖，排名2
［1］Topological, reorganization of brain functional networks in patients with mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes. NeuroImage: Clinical,2020 .(IF=4.35，通讯作者)
［2］Multiparametric MRI-Based Radiomics Model for Differentiating Primary Central Nervous System Lymphoma From Glioblastoma: Development and Cross-Vendor Validation. Journal of Magnetic Resonance Imaging,2020. (IF=3.954，通讯作者)
［3］Altered Dynamic Functional Connectivity in Patients With Mitochondrial Encephalomyopathy With Lactic Acidosis and Stroke-Like Episodes (MELAS) at Acute and Chronic Stages: Shared and Specific Brain Connectivity Abnormalities. Journal of Magnetic Resonance Imaging,2020. (IF=3.954，通讯作者)
［4］Screening for Early-Stage Parkinson’s Disease: Swallow Tail Sign on MRI Susceptibility Map-Weighted Images Compared With PET. Journal of Magnetic Resonance Imaging,2020. (IF=3.954，通讯作者)
［5］Short-echo-time magnitude image derived from quantitative susceptibility mapping could resemble neuromelanin-sensitive MRI image in substantia nigra, BMC Neurology, 2020. (IF=2.233，通讯作者)
［6］ Brain MRI features of Chinese Han patients with MOG-antibody disease, Multiple Sclerosis and Related Disorders,2020. (IF=2.889，通讯作者)
［7］Swallow tail sign on susceptibility map-weighted imaging (SMWI) for disease diagnosing and severity evaluating in parkinsonism. Acta Radiologica,2020. (IF=1.461，通讯作者)
［8］Quantitative brain lesion distribution may distinguish MOG-ab and AQP4-ab neuromyelitis optica spectrum disorders, European Radiology,2019 (IF=4.101，通讯作者)
［9］Radial diffusivity as an imaging biomarker for early diagnosis of non-demented amyotrophic lateral sclerosis. Eur Radiol. 2018. (IF=3.962，通讯作者)
［10］ Current Insight Into MELAS: Clinical Perspectives and Multimodal MRI, J Magn Reson Imaging, 2018. (IF=3.732，第一作者)
［11］Evaluation of patients with relapsing-remitting multiple sclerosis using tract-based spatial statistics analysis: diffusion kurtosis imaging. BMC Neurol. 2018. (IF=2.233，通讯作者)
［12］Conventional and Diffusional Magnetic Resonance Imaging Features of Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes in Chinese Patients: A Study of 40 Cases, J Comput Assist Tomogr, 2018. (IF=1.301，通讯作者)
［13］Cerebral cortical encephalitis followed by recurrent CNS demyelination in a patient with concomitant anti-MOG and anti-NMDA receptor antibodies. Mult Scler Relat Disord. 2017 . (IF=3.199，通讯作者)
［14］ Increased Cerebral Blood Flow as a Predictor of Episodes in MELAS Using Multimodal MRI, J Magn Reson Imaging, 2017. (SCI, IF=3.732，通讯作者)
［15］Reversible dialation of cerebral macrovascular in MELAS episodes, Clin Neuroradio,2017.(IF=2.8，第一作者)
